In heart disease, cardiac muscle gradually dies off and, with little or no way to regenerate those cells, that can ultimately lead the heart to fail. But scientists reporting in the August 6th issue of Cell, a Cell Press publication, might have found a way to fix those losses. They've devised a three-ingredient molecular cocktail that transforms fibroblasts - structural cells that the heart is chock full of - directly into beating heart cells.
Growth hormone is used to treat children's growth disorders and has been used by some sports men and women to promote muscle growth and regeneration. This is because it coordinates skeletal muscle development, nutrient uptake, and nutrient utilization. It is not clear, however, which of these effects are direct and which are indirectly mediated via growth hormone induction of the protein IGF-1.
For Popeye, spinach was the key to extra muscle. For the mice in a new University of Iowa study, it was apples, or more precisely a waxy substance called ursolic acid that's found in apple peel.
A study conducted by Children's Hospital & Research Center Oakland scientists identifies how skeletal muscle stem cells respond to muscle injury and may be stimulated to improve muscle repair in Duchenne Muscular Dystrophy, a severe inherited disease of muscle that causes weakness, disability and, ultimately, heart and respiratory failure.
The size of muscles in patients suffering from Chronic Kidney Disease could be more important to maintaining good physical performance than muscle quality, new research has shown.
Taking daily recommended dosages of ibuprofen and acetaminophen caused a substantially greater increase over placebo in the amount of quadriceps muscle mass and muscle strength gained during three months of regular weight lifting, in a study by physiologists at the Human Performance Laboratory, Ball State University.
Hey guys, remember the muscle shirts we wore in our teens and 20s? After the age of 40 that meager part of our wardrobes usually is obsolete. Yes, at the big 4-0 we begin to lose muscle, and by age 80 up to a third of it may be gone. It's an inevitable process of aging called sarcopenia.
A study published today in BioMed Central's open access journal Skeletal Muscle reports of a new therapeutic technique to repair and rebuild muscle for sufferers of degenerative muscle disorders. The therapy brings together two existing techniques for muscle repair - cell transplantation and tissue engineering - specifically, mesoangioblast stem cells delivered via a hydrogel cell-carrier matrix.