Infertility is common among obese women, but the reasons remain poorly understood and few treatments exist. Now a team of Johns Hopkins Children's Center scientists, conducting experiments in mice, has uncovered what they consider surprising evidence that insulin resistance, long considered a prime suspect, has little to do with infertility in women with type-2 diabetes, polycystic ovary syndrome and metabolic syndrome, all obesity-related conditions.
For the first time, Massachusetts General Hospital (MGH) researchers have isolated egg-producing stem cells from the ovaries of reproductive age women and shown these cells can produce what appear to be normal egg cells or oocytes.
Researchers may have found a way to end menopause after proving that transplanted ovaries remain effective for at least seven years. Of the three women, one has had three children since her transplant, a second has had two and the third is expecting her third child. Medical experts believe the three could be the pioneers for a treatment that would allow women to delay motherhood.
A proof-of-concept study suggests the possibility of engineering artificial ovaries in the lab to provide a more natural option for hormone replacement therapy for women.
It was known till now that women were born with all the eggs they'll ever have. But now Harvard scientists have found that ovaries of young women harbor very rare stem cells capable of producing new eggs. The researchers feel that harnessing those stem cells might one day lead to better treatments for women left infertile because of disease or age.
Hysterectomy elevates the risk of stroke and coronary heart disease in young women when combined with the removal of both ovaries in the same operation. This fact provides the background for the epidemiological report by Andreas Stang and colleagues on hysterectomy rates in Germany, which appears in the current issue of Deutsches Ärzteblatt International.
Presurgical and surgical factors, and postsurgical pain intensity, should be taken into account when providing rescue analgesia to women after hysterectomy, researchers say.
OvaScience, a fertility company focused on the discovery, development and commercialization of novel treatments for infertility, today announced the publication of results demonstrating that ovaries of reproductive-age women possess egg precursor cells that can mature into eggs.